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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
10.91
Human Site:
S458
Identified Species:
18.46
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S458
E
V
P
H
G
S
Q
S
S
E
S
F
Q
F
Q
Chimpanzee
Pan troglodytes
XP_509445
540
59236
F297
Q
S
S
E
S
F
Q
F
Q
P
P
L
P
P
D
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S458
E
V
P
H
G
S
L
S
S
E
T
F
Q
F
Q
Dog
Lupus familis
XP_534658
709
78944
S458
E
V
P
H
S
S
P
S
G
A
F
Q
F
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
S461
I
P
P
G
S
Q
S
S
K
A
F
Q
F
Q
P
Rat
Rattus norvegicus
NP_001099399
476
51796
E233
M
E
L
D
S
D
I
E
I
P
P
G
S
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
S455
E
V
P
P
S
S
H
S
G
E
A
F
E
F
Q
Chicken
Gallus gallus
Q5F3D1
613
68449
S370
P
P
G
P
P
V
I
S
T
P
P
P
L
P
Q
Frog
Xenopus laevis
Q6DD45
743
82926
Y443
M
E
S
D
E
D
M
Y
H
S
R
A
S
K
G
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
P442
S
D
G
F
Q
F
H
P
P
L
P
P
G
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
V310
K
Y
D
V
N
K
I
V
E
Y
P
G
F
N
V
Honey Bee
Apis mellifera
XP_001122586
556
62911
D313
P
P
G
T
R
D
E
D
G
Q
Y
W
I
S
R
Nematode Worm
Caenorhab. elegans
P34656
453
51815
D210
R
K
S
I
K
S
T
D
Q
L
K
F
F
D
S
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
I383
S
S
Q
K
K
R
R
I
E
K
D
S
V
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
6.6
86.6
40
N.A.
13.3
0
N.A.
60
13.3
0
0
N.A.
0
0
13.3
0
P-Site Similarity:
100
13.3
93.3
40
N.A.
13.3
0
N.A.
73.3
20
0
0
N.A.
6.6
26.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
15
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
15
0
22
0
15
0
0
8
0
0
15
8
% D
% Glu:
29
15
0
8
8
0
8
8
15
22
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
15
0
8
0
0
15
29
29
22
0
% F
% Gly:
0
0
22
8
15
0
0
0
22
0
0
15
8
0
8
% G
% His:
0
0
0
22
0
0
15
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
22
8
8
0
0
0
8
0
0
% I
% Lys:
8
8
0
8
15
8
0
0
8
8
8
0
0
8
0
% K
% Leu:
0
0
8
0
0
0
8
0
0
15
0
8
8
0
0
% L
% Met:
15
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
15
22
36
15
8
0
8
8
8
22
36
15
8
15
15
% P
% Gln:
8
0
8
0
8
8
15
0
15
8
0
15
15
22
29
% Q
% Arg:
8
0
0
0
8
8
8
0
0
0
8
0
0
0
8
% R
% Ser:
15
15
22
0
36
36
8
43
15
8
8
8
15
8
22
% S
% Thr:
0
0
0
8
0
0
8
0
8
0
8
0
0
8
0
% T
% Val:
0
29
0
8
0
8
0
8
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _